Horse/Equine
Take a double handful of Bran
Moisten it ( water and molasses )
Mix the joint rejuvenate powder with the moistened bran
Mix this with the rest of the feed

Dog/Canine
Mix with a spoonful of canned food
Some like it in milk

Cat/Feline
Mix with a spoonful of canned food
Some like it in milk

Dogs and cats: 20 to 60 mg/kg as a treatment dose

Horses: 2m/kg Prevention
6-10 mg/kg Early stage joint wear and tear manifest by stiffness
20 mg/kg Moderate stage joint wear and tear manifest by subtle lameness 20mg/kg

2 to 8 weeks in dogs,cats and horses. The most important thing to appreciate is that you are not going to see quick improvement the next day the way you would do if you took aspirin or meloxicam or phenylbutazone. We suggest using a double dose for 14 days. 

If you have seen no improvement after 14 days you are only a 20% chance of seeing improvement even if you persist for the recommended 8 weeks.